The concomitant utilization of TYLENOL® with Codeine with all CYP3A4 inducers or discontinuation of the CYP3A4 inhibitor may well lead to reduced codeine degrees, better norcodeine concentrations, and fewer metabolism by way of CYP2D6 with resultant reduce morphine degrees.Cold, clammy pores and skin dry mouth fainting no hypertension or pulse no